VariantBench: explore and filter VCF files

VariantBench opens VCF and gzipped VCF files directly in your browser, summarizes the variants, reads SnpEff or VEP annotations, and lets you filter down to what matters and export the result.

Open VariantBench All tools

Free, no sign-up, and installable on your phone. Runs in your browser at variants.gataca.com.

VariantBench showing results for the built-in example — VariantBench with its built-in example loaded.

What you can do with VariantBench

Review variant calls from a sequencing run without the command line
Pull out high-impact variants in a gene of interest
Check call quality with Ti/Tv ratio and QUAL distribution
Share a filtered subset of variants with a collaborator

How to use it

Choose a .vcf or .vcf.gz file, or paste VCF text.
Review the summary: variant counts, types, Ti/Tv, and quality.
Filter by chromosome, type, impact, QUAL, gene, or a sample's genotype.
Export the filtered variants as a standard VCF file.

Features

Reads VCF and gzip-compressed VCF
SnpEff ANN and Ensembl VEP CSQ annotation parsing
Variant type, per-chromosome, and quality summaries
Transition/transversion (Ti/Tv) ratio
Filters by gene, impact, QUAL, PASS, and genotype
Export filtered variants as VCF
Save results as reports, spreadsheets, or sequence files
Install it on your phone or computer; works offline

Frequently asked questions

Is it safe to open patient data?

Files are read and processed only in your browser and are never uploaded. Follow your institution's data policies for where such files may be opened.

What does the Ti/Tv ratio tell me?

It's a quick quality check. Whole-genome human calls typically show a ratio around 2.0 to 2.1, and exome calls around 2.8 to 3.0; much lower values can indicate false positives.

Does it support structural variants?

Symbolic alleles like DEL and DUP are loaded and counted as Other. Detailed SV visualization is not included.